4/14/2023 0 Comments Symptoms of adrenal gland tumorAlthough there are radiological (e.g., intratumor necrosis, irregular margins, and local metastases), histopathological (e.g., Weiss criteria), and genetic (e.g., overexpression of IGF2 and loss of heterozygosity at 17p13) criteria to predict malignancy, no absolute specific marker and feature exist to reliably distinguish benign and malignant adrenal lesions, excluding pure adrenal ganglioneuroma, which by definition is always benign. Assessing such patients for the presence of subclinical disease caused by adrenal incidentalomas and the potential for malignancy is challenging. Modern imaging modalities facilitate better detection of adrenal masses than in the past but also detect adrenal incidentalomas in patients who are not evaluated for adrenal tumors. Chrousos, in Encyclopedia of Endocrine Diseases, 2004Īdrenal tumors are found in up to 9% of autopsy studies.
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